Animal Researche: 18pt;">Indian goosebery fruit may support overall health.
Amla is a herb widely utilized in traditional Indian medicine and cuisine. As a green food supplement, it may have such benefits as:
- Antioxidant activity. Amla contains potent antioxidant compounds.
- Improved cardiovascular health. Amla has been shown to reduce elevated blood sugar, pressure, and cholesterol levels.
- Supplying nutrients. Amla is a good source of vitamin C, iron, and other nutrients.
Emblica officinalis, also known as Phyllanthus emblica, Indian gooseberry, or by its Hindu name amla, is a tropical tree prized for its nutritional and medicinal value. Amla’s yellowish-green berries are commonly eaten raw or used to prepare various sweet foods. The fruit is a rich source of vitamin C and minerals such as iron and phosphorus, as well as numerous bio-active compounds such as the polyphenols gallic and ellagic acid, and the flavonoids rutin and quercetin.
Outside of its dietary use, amla is utilized by traditional Ayurvedic medicine to help with diabetes, osteoporosis, inflammatory, neurological, and cardiovascular conditions, promote longevity, improve digestion, and much more. Amla oil and powder is also used topically to enhance hair and skin health.
Clinical research has reported on multiple beneficial properties of amla, including: 1
Like many other tropical herbs advertised as a nutrient-dense superfood, amla is quickly growing in popularity as a green food supplement purported to support overall health.
How Amla Might Improve Your Health
Amla preparations have been shown to work through multiple biological mechanisms; however, the two most important ones seem to be:
Amla’s rich supply of antioxidant compounds is believed to be the major mechanism through which it provides many of its beneficial effects. Indeed, oxidative stress is involved in a wide range of health disorders, including conditions treated by amla such as sun damage to the skin, Alzheimer’s, and diabetes. 2
Anti-inflammatory and immunomodulatory activity
Inflammation is a key part of the body’s immune response, but its dysfunction plays a role in a wide range of inflammatory and autoimmune disorders. Amla has been shown to affect immune system function and reduce inflammation in cell culture and animal research through inhibiting pro-inflammatory pathways such as NF-κB as well as inflammatory cytokines.3 4<
Amla’s Potential Uses & Benefits
Amla is sold as a green powder supplement purported to have many benefits, including increased energy levels, improved digestion, and rejuvenation of overall health. Some people also use it for arthritis, diabetes, regulating cholesterol levels, and various other conditions. In addition, amla is also applied topically as a skin care product used to protect and heal the skin, and as a hair care product.
Although amla’s generic health claims have not been tested by research, there is a much evidence for its specific effects such as antioxidant & anti-inflammatory activity, reduction of blood sugar and cholesterol, protection of skin against sun damage, and neuroprotection. However, most of this evidence is currently restricted to cell culture and animal studies.
Amla has been extensively examined in cell culture and animal studies. Findings indicate that amla has a wide array of beneficial properties, including:
- Potent antioxidant activity 5 6
- Alleviation of osteoarthritis and rheumatoid (autoimmune) arthritis through chondroprotective activity 7 8
- Protection against memory deficits, dementia, Alzheimer’s, and other neurodegenerative conditions 9 10
- Protection against gastrointestinal tract disorders in rats 11
- Stimulation of the immune system, which helped improve immunity against parasitic infection in chickens 12
- Antimicrobial activity that may help fight infectious bacteria and fungi 13
- Protection of skin when applied topically as an anti-aging, sunscreen, and wound healing product 14 15
- Alleviation of hyperthyroidism in mice 16
In this study, healthy and diabetic adults were given amla fruit powder (1,2, or 3 g) daily for 21 days to test its effects on blood sugar and lipids. Both groups saw a decrease in fasting and post-meal blood sugar levels, in addition to reduced levels of cholesterol, triglycerides, LDL (“bad”) cholesterol, and increased levels of HDL (“good”) cholesterol.
- The researchers concluded that “Both normal and diabetic volunteers receiving 2 or 3 g E. officinalis powder significantly (P < 0.05) improved high-density lipoprotein-cholesterol and lowered low-density lipoprotein-cholesterol levels.” 17
Eighty type 2 diabetics were given placebo, atorvastatin, or amla extract daily (500 or 1000 mg) for 12 weeks in randomized, double-blind, placebo-controlled study. Both amla groups improved in endothelial function – a measure of cardiovascular health – and had lowered levels of oxidative stress and inflammation.
- The researchers concluded that “…P. emblica significantly improved endothelial function and reduced biomarkers of oxidative stress and systemic inflammation in patients with type 2 diabetes mellitus.”18
The goal of this study was to examine the benefits of amla in people with hyperlipidemia (high cholesterol). Sixty type II hyperlipidemics were given amla extract (500 mg) or simvastatin (20 mg) daily for 42 days. Amla supplementation was found to improve blood lipid levels and decrease blood pressure.
- The researchers concluded that “Addition of Amla to the currently available hypolipidemic therapy would offer significant protection against atherosclerosis and coronary artery disease.” 19
This study examined the effects of amla on cardiovascular disease risk factors (CVD). For 12 weeks, 15 overweight or obese adults were given 500 mg (twice daily) of CAPROS, a supplement derived from amla fruit. The supplementation improved three measures of CVD: blood lipid levels, Circulatory high-sensitivity C reactive protein (hs-CRP) levels, and platelet aggregation.
- The researchers concluded that “oral CAPROS supplementation may provide beneficial effects in overweight/Class-1 obese adults by lowering multiple global CVD risk factors.” 20
Supplements in Review Saysl>
Amla may help support overall health. Similar to other so-called superfood herbs such as moringa and spirulina, amla contains nutrients and phytochemicals capable of benefiting your health. So far, however, only its anti-diabetic and cardiovascular benefits have been confirmed in humans.
Amla powder at doses of 1 – 5 g seems ideal. Like most greens, amla seems best taken in its powder form, typically mixed together with a drink or yogurt. In addition, it can also be applied topically on the skin and hair.
- Bhavesh C. Variya, Anita K. Bakrania, Snehal S. Patel, Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms, Pharmacological Research, Volume 111, 2016, Pages 180-200. ↩
- D’souza JJ et al. Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action. Food Funct. 2014 Apr;5(4):635-44. ↩
- Golechha M et al. Anti-Inflammatory Effect of Emblica officinalis in Rodent Models of Acute and Chronic Inflammation: Involvement of Possible Mechanisms. International Journal of InflammationVolume 2014 (2014), 6 p. ↩
- https://www.mskcc.org/cancer-care/integrative-medicine/herbs/emblica-officinalis ↩
- Scartezzini P et al. Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn. J Ethnopharmacol. 2006 Mar 8;104(1-2):113-8. ↩
- Bhattacharya A et al. Antioxidant activity of active tannoid principles of Emblica officinalis (amla). Indian J Exp Biol. 1999 Jul;37(7):676-80. ↩
- Sumantran VN et al. Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis. Evid Based Complement Alternat Med. 2008 Sep;5(3):329-35. ↩
- Penolazzi L et al. Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis. BMC Complement Altern Med. 2008 Oct 30;8:59. ↩
- Vrish D et al. Reversal effect of Phyllanthus emblica (Euphorbiaceae) rasayana on memory deficits in mice. Int J of App Pharm. 2011;3(2). ↩
- Uddin MS et al. Exploring the Effect of Phyllanthus emblica L. on Cognitive Performance, Brain Antioxidant Markers and Acetylcholinesterase Activity in Rats: Promising Natural Gift for the Mitigation of Alzheimer’s Disease. Ann Neurosci. 2016 Oct;23(4):218-229. ↩
- Al-Rehaily AJ et al. Gastroprotective effects of ‘Amla’ Emblica officinalis on in vivo test models in rats. Phytomedicine. 2002 Sep;9(6):515-22. ↩
- Kaleem QM et al. Studies on Emblica officinalis derived tannins for their immunostimulatory and protective activities against coccidiosis in industrial broiler chickens. ScientificWorldJournal. 2014 Jan 22;2014:378473. ↩
- Kumar A et al. Comparative study of antimicrobial activity and phytochemical analysis of methanolic and aqueous extracts of the fruit of Emblica officinalis against pathogenic bacteria. J Tradit Chin Med. 2011 Sep;31(3):246-50. ↩
- Sumitra M et al. Emblica officinalis exerts wound healing action through up-regulation of collagen and extracellular signal-regulated kinases (ERK1/2). Wound Repair Regen. 2009 Jan-Feb;17(1):99-107. ↩
- Chaudhuri RK. Emblica cascading antioxidant: a novel natural skin care ingredient. Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):374-80. ↩
- Panda S and Kar A. Fruit extract of Emblica officinalis ameliorates hyperthyroidism and hepatic lipid peroxidation in mice. Pharmazie. 2003 Oct;58(10):753-5. ↩
- Akhtar MS et al. Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011 Sep;62(6):609-16. ↩
- Usharani P et al. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 2013; 6: 275–284. ↩
- Gopa B et al. A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin. Indian J Pharmacol. 2012 Mar-Apr; 44(2): 238–242. ↩
- Khanna S et al. Supplementation of a Standardized Extract from Phyllanthus emblica Improves Cardiovascular Risk Factors and Platelet Aggregation in Overweight/Class-1 Obese Adults J Med Food. 2015 Apr 1; 18(4): 415–420. ↩