Supplements in Review

  • Protein
  • Nootropic
  • Testosterone
  • Fat Loss
  • Pre-Workout
  • Vision
  • Sleep
  • More Categories…
    • Greens
    • Energy
    • Immune
    • Stress
    • Joints
    • Post-Workout
    • Growth Hormone
    • Multi
    • Brands
  • Blog
You are here: Home / Joints / Exploring Joint Supplements for Effective Osteoarthritis Relief

Exploring Joint Supplements for Effective Osteoarthritis Relief

May 9, 2024 By Valentino Muža Leave a Comment Last Updated: June 10, 2024

A bottle of brown herbal pills lying on a yellow surface.
Photo by Karolina Grabowska.

Osteoarthritis is a major problem in our society.

This condition not only slows us down; it also limits our way of life.

But there is good news.

There are ways to combat osteoarthritis and its symptoms, including taking targeted joint supplements.

Many natural joint supplements have been shown to ease pain, improve mobility, and protect long-term joint health.

In this SiR article, I break down how they work, what results you can expect from taking these supplements, and how to pick the right one for you.

Ready to dive in?

Table of Contents

Toggle
  • About Osteoarthritis
  • Key Supplements for Osteoarthritis Relief
    • Boswellia Serrata
    • Glucosamine+Chondroitin
    • Curcumin
    • MSM
    • Omega-3s
    • Collagen
    • Hyaluronic Acid
  • Notable Studies
  • Ending Notes
  • References

About Osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease. This means that the tissues in joints – particularly, cartilage – break down over time.

As cartilage that cushions the joints degrade, bones might start rubbing against each other, which results in discomfort.

OA is the most common type of arthritis and is more common in older people. Symptoms include pain in hands, knees, hips, feet, and other joints, as well as stiffness and aches when moving after a period of inactivity.

While there is no known cure for OA in the medical world, there are many ways we can combat it, ranging from physical therapy, to taking medications, to using joint supplements aiding osteoarthritis relief.

A young woman putting a white band aid around a young man's leg just above his ankle.
Photo by Pexels.

Key Supplements for Osteoarthritis Relief

Boswellia Serrata

Boswellia Serrata is a type of tree resin, also known as Indian Frankincense. It is often supplemented for its natural analgesic properties. It’s been shown to significantly alleviate pain, stiffness, and other OA symptoms.

According to some users, Boswellia might be one of the most potent natural osteoarthritis relief supplements out there.

Glucosamine+Chondroitin

Glucosamine and chondroitin are both natural molecules that make up our joints. They are important for maintaining and repairing cartilage, hydrating connective tissues, as well as keeping your joints resilient against physical impacts such as exercise.

The problem is, glucosamine and chondroitin levels may go down as we age, due to various factors. This can result in faster cartilage breakdown, aggravating osteoarthritis progress, and by consequence—symptoms.

Many people supplement glucosamine and chondroitin to replenish their waning levels. While studies are inconclusive, some suggest that doing so might help to relieve stiffness and pain in osteoarthritis.

Curcumin

Curcumin is the active component of the turmeric spice. Its potent anti-inflammatory properties are suggested to rival those of non-steroidal anti-inflammatory drugs (NSAIDs).

In addition to potentially lowering joint inflammation—which causes pain, swelling and wears cartilage down—curcumin also has antioxidant and other healthful activities. This makes curcumin one of the most popular options for OA sufferers.

MSM

MSM is a type of sulfur naturally found in plants, animals, and humans. It can also be made in a lab. It plays an important role in maintaining joint health.

When supplemented, MSM may exert antioxidant and joint-protective effects. Many people swear by MSM for osteoarthritis pain reduction. Studies tend to support its use as a safe and effective joint relief supplement.

Omega-3s

Omega-3 fatty acids (EPA and DHA) are powerful anti-inflammatory ingredients found in fish and some plant sources (like algae).

They combat pro-inflammatory chemicals, including eicosanoids and cytokines. You may notice improved joint function as well as less pain and stiffness as a result.

Collagen

With its fiber-like structure, collagen is the most abundant protein in our body, used for making connective tissue.

There are different types of collagen, many of which are shown to benefit joint health to an extent. But in the context of osteoarthritis, type-II collagen has been shown to reduce inflammation and other symptoms.

Hyaluronic Acid

Hyaluronic acid (HA) is a unique joint supplement because it’s naturally found in our joint fluid, where it serves as lubricant and shock absorber.

Some people take HA injections to relieve joint pain. But even oral intake is demonstrated to reduce knee and other types of pain in osteoarthritis.

Notable Studies

  • MSM Improves Symptoms of Pain and Physical Function in OA1

First up is a 2005 randomized, double-blind, placebo-controlled trial. It included fifty men and women aged 40-76. All of these people had knee osteoarthritis.

They were split into two groups: one took 3 grams of MSM powder twice per day, and the other group took a placebo, every day for 12 weeks.

At the end of the study, the MSM group’s results showed saw significant improvements in pain and physical function, as well as an improvement in activities of daily living, compared to people who took a placebo.

  • Curcumin Aiding Knee Osteoarthritis Treatment2

This 2024 meta-analysis looked at 23 randomized controlled trials from 7 countries that investigated curcumin’s effects on knee osteoarthritis.

After examination, the researchers found that “curcumin, either alone or in combination with other treatments, is considered to have good clinical efficacy and safety in KOA treatment. Drug combinations containing curcumin may have the dual effect of enhancing efficacy and reducing adverse reactions, but this possibility still needs to be confirmed by further clinical and basic research.”

Ending Notes

To make sure the joint supplement is effective, high-quality, and safe, you need to check its ingredients, company reputation, and reviews online.

The product should be third-party tested and made in cGMP and/or FDA-approved facilities.

The ingredients should be clearly shown on the label, as well as their dosages. Avoid proprietary blends where you can only see the total amount of ingredients combined!

The most effective joint supplements are more expensive than average since they contain multiple premium ingredients in higher dosages. But you can also find decent budget-friendly options.

Just make sure to do thorough research, because the effectiveness and safety of a supplement depends largely on what it uses and in what amounts.

Further Reading:

  • Exploring Supplements Role in Osteoarthritis Relief
  • Exploring the Impact of Joint Supplements on Senior Osteoarthritis Relief
  • Exploring Natural Joint Supplements for Osteoarthritis Relief
  • Tailoring Joint Supplement Regimens for Advanced Osteoarthritis Management
  • Joint Supplements for Active Seniors With Osteoarthritis

References

  1. Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. doi: 10.1016/j.joca.2005.10.003. Epub 2005 Nov 23. PMID: 16309928. ↩︎
  2. Zhao J, Liang G, Zhou G, Hong K, Yang W, Liu J, Zeng L. Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis. J Ethnopharmacol. 2024 Mar 1;321:117493. doi: 10.1016/j.jep.2023.117493. Epub 2023 Nov 28. PMID: 38036015. ↩︎

Filed Under: Joints

Leave a Reply

Your email address will not be published. Required fields are marked *

Find us on Facebook

Supplements in Review

About the director

My name is Valentino Muza, and I am the managing director and lead author at Supplements in Review. I am responsible for content production of the website. Read more about Valentino...

Recently Added

  • My Performance Lab Omega-3 Review [Updated]
  • Top Nootropic Supplements for 2025
  • Salt Wrap Joint Clinic Review – Does it Work?
  • Joint Supplements for Active Seniors With Osteoarthritis
  • Zenwise Joint Support Review: Does it Work?
  • Omega XL vs Omega 3: Which is Better?
  • Life Seasons Mobili-T Review
  • Tailoring Joint Supplement Regimens for Advanced Osteoarthritis Management
  • Exploring Natural Joint Supplements for Osteoarthritis Relief
  • Exploring the Impact of Joint Supplements on Senior Osteoarthritis Relief

Book cover of Health Shining Bright by Valentino Muža

Sign up to my email newsletter and receive a free eBook: “Health Shining Bright.”

  • Amazon
  • Facebook
  • Instagram
  • LinkedIn
  • Twitter

Press contact information

valentino@supplementsinreview.com

info@supplementsinreview.com

Disclaimer

* These statements have not been evaluated by the Food and Drug Administration. The products mentioned anywhere on Supplements in Review are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.

Copyright © 2025 · Supplements in Review · Contact Us · Disclaimer

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok