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You are here: Home / Multi / Vitamin B7 in Multivitamins

Vitamin B7 in Multivitamins

April 19, 2017 By Leave a Comment Last Updated: April 23, 2017

Multivitamins contain modest amounts of vitamin B7 given its role in energy metabolism and other vital processes.

Vitamin B7, molecular structure. By User:Mysid [Public domain], via Wikimedia Commons
Vitamin B7 is essential to numerous essential biological processes in the body, but is most widely recognized for its involvement in:

  • Energy metabolism. Vitamin B7 helps produce and utilize fats, glucose, and amino acids.

Table of Contents

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  • Overview
    • Recommended Dietary Allowances (RDAs) for Vitamin B7
    • Foods High in Vitamin B7
  • How Vitamin B7 Supports General Health
    • Biotinylation
  • Vitamin B7’s Benefits as a Multivitamin
  • Multivitamin Dosage
  • Supplements in Review Says

Overview

Vitamin B7, more popularly called biotin, is a water-soluble B vitamin that aids the function of enzymes involved in the synthesis and utilization of fatty acids, glucose, and the branched chain amino acids leucine, isoleucine and valine.1 It’s also involved in cell growth, the transfer of carbon dioxide, and other processes.

Whereas the indispensable vitamin is naturally made by some types of bacteria, yeast, and plants, people need to consume it as a part of their diet. Some of the easy-to-access foods containing vitamin B7 include egg yolk, whole grain cereal, and produce such as bananas and avocados. Vitamin B7 deficiency and insufficiency are relatively rare.

Did you know? Vitamin B7 was previously called vitamin H, and before that, coenzyme R.

Recommended Dietary Allowances (RDAs) for Vitamin B7

AgeMalesFemales
 0 – 12 months 7 mcg 7 mcg
 1 – 8 years 8 – 12 mcg 8 – 12 mcg
 9 – 13 years 20 mcg 20 mcg
 14 – 18 years25 mcg  25 mcg (30 mcg for pregnancy, 35 mcg for breast-feeding)
 19+ 30 mcg  30 mg (30 mcg for pregnancy, 35 mcg for breast-feeding)

Foods High in Vitamin B7

FoodServing SizeAmount per serving (mcg)
Bananas 1 fruit (~100 grams)118
 Peas (dried) 2/3 cup (100 grams)70
 Sunflower seeds 2/3 cup66
 Rice bran 2/3 cup66
 Barley2/3 cup31
Oatmeal 2/3 cup24
Unlike most fruits, bananas carry a relatively high amount of biotin at 118 mcg. Steve Hopson, [CC BY-SA 2.5], via Wikimedia Commons

How Vitamin B7 Supports General Health

Vitamin B7 participates in a variety of critical bodily processes, but its major role is:

Biotinylation

In a mechanism referred to as biotinylation, vitamin B1 binds to and activates five enzyme groups necessary for the production and utilization of sugars, fatty acids, and amino acids:

  • Acetyl-Coenzyme A carboxylase 1 (ACC1) and acetyl-CoA carboxylase 2 (ACC2) both help generate acetyl-coenzyme A (CoA), which is ultimately used to produce energy for the body
  • Pyruvate carboxylase plays a part in making glucose, which is subsequently used to produce energy for the body
  • Methylcrotonyl-CoA carboxylase helps break down the essential amino acid leucine so that it can be turned into energy via the citric acid cycle
  • Propionyl-CoA carboxylase is similarly required to break down other amino acids for energy production
One peculiar risk factor for vitamin B7 deficiency is consumption of raw egg whites, which contain a protein known as avidin that binds to vitamin B7 and prevents its absorption.

Vitamin B7’s Benefits as a Multivitamin

Hair loss is one of the most common symptoms of biotin deficiency. By Докторъ (Own work) [Public domain], via Wikimedia Commons
Although insufficient vitamin B7 levels are a rare occurrence, this essential nutrient is still added to multivitamins to provide a form of nutritional insurance. In this way, you can make sure you get enough B7 to support its role in energy production and other essential processes.

There is also some early evidence that vitamin B7 supplementation can help with brittle nails and hair loss, but conclusive research evidence is lacking.  2 3 4 5

Vitamin B7 may help with multiple sclerosis. By facilitating the synthesis of myelin, the protective layer surrounding neurons, vitamin B7 may limit the development of neural health complications such as multiple sclerosis.6

Multivitamin Dosage

  • Multivitamins incorporate a wide range of vitamin B7, anywhere from 30 – 10,000 mcg
  • Health professionals recommend no more than 10,000 mcg of vitamin B7

Supplements in Review Says

  • Vitamin B7 30 mcg as part of a multivitamin.

Vitamin B7 is needed for proper energy production and other essential processes. As other B vitamins, B7 plays a critical part in energy metabolism and other essential biological reactions, warranting its inclusion in multivitamin supplements.

A daily dose of 30 mcg is recommended by NIH. Although multivitamins can contain doses as high as 10,000 mcg, you only need to make sure that your multivitamin contains at least 30 mcg to meet your daily needs.

Show 6 footnotes

  1. Bonjour JP. Biotin in human nutrition. Ann N Y Acad Sci. 1985;447:97-104. ↩
  2. Famenini S, et al. Evidence for supplemental treatments in androgenetic alopecia. J Drugs Dermatol. 2014;13(7):809-12. ↩
  3. Bolander FF. Vitamins: not just for enzymes. Curr Opin Investig Drugs. 2006 Oct;7(10):912-5. ↩
  4. Colombo VE, et al. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol. 1990 Dec;23(6 Pt 1):1127-32. ↩
  5. Hochman LG. Brittle nails: response to daily biotin supplementation. Cutis. 1993 Apr;51(4):303-5. ↩
  6. Sedel F, et al. Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis. Neuropharmacology. 2016 Nov;110(Pt B):644-53. ↩

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