Akarkara root has shown the ability to boost testosterone and enhance sexual health in animal studies.
Akarkara is a herb with a rich history of use for the male reproductive system. Its specific potential uses for male sexual health include:
- Boosting testosterone levels. Akarkara has been to act as a testosterone (T) booster in animals.
- Enhancing virility. Libido, sperm count, and general sexual function seem to be enhanced by akarkara use.
Akarkara (Anacyclus pyrethrum) is a plant native to North Africa, Northern India, and select regions around the Mediterranean, whose name has been popularized from the original Hindi “akkal kara”. The most prized component of akarkara is its tough root, which has been incorporated into traditional medicine practices for centuries.
- Antimicrobial activity
- Anti-inflammatory activity
- Antidepressant activity
- Anti-convulsant activity
- Immunostimulating capacity2
Its best known use, however, has been as an aphrodisiac and fertility enhancer. It seems to impart a myriad of positive health effects on the male reproductive system, including increased testosterone levels.
How Akarkara Might Help With Testosterone
The primary bioactive ingredients in akarkara roots are known as alkylamides, namely anacyclin and pellitorine. They are believed to boost testosterone levels, although specific biological pathways have yet to be identified.
Stimulating hormone release
The alkylamides found in akarkara roots may increase testosterone production by stimulating the release of the gonadotropins: follicle stimulating hormone (FSH) and luteinizing hormone (LH), which in turn, activate spermatogenesis and promote the synthesis and release of testosterone.3
Akarkara Benefits & Uses for Testosterone
Akarkara is believed to have a plethora of benefits related to masculinity, including4:
- Increasing libido
- Increasing sperm count and sperm motility
- Promoting fertility
- Boosting testosterone levels
Animal studies demonstrate that akarkara is capable of increasing testosterone levels as well as some fertility and sexual function parameters.
In this investigation, 60 male rats were injected daily with 50, 100, or 150 mg/kg body weight of an akarkara aqueous root extract for a 28-day period. The treatment significantly elevated levels of gonadotropin hormone (LH, FSH) and testosterone compared to the control group.
- The researchers concluded that “the aqueous extract root of A. pyrethrum has compounds that could directly or indirectly promote testosterone to increase reproductive activity.”6
In this investigation, male rats were given 50, 100, or 150 mg/kg body weight of akarkara extract for a period of 28 days. All doses of akarkara were found to trigger significant increases in body weight, testosterone, FSH, LH, and sperm count, motility, and viability. Increased spermatogenic activity was also visible in its histoarchitecture.
- The researchers concluded that “the ethanol solution extract of the roots of A. pyrethrum has androgenic potential and may improve male fertility by enhancing spermatogenesis.”7
In this investigation, 32 male rats were administered testosterone or either 50 or 100 mg/kg body weight of akarkara extract every day for 28 days. Both akarkara and testosterone groups were found to have increases in accessory sexual organ weights. Compared to testosterone, akarkara treated male rats were more receptive toward female rats, had significantly increased penile erection indices, and up to 4 times the frequency of sexual intercourse. These effects were observed until 15 days after discontinuance of drug treatment.
- The researchers concluded that “the drug has prolonged effect and capacitate the treated rats for improved sexual potential.”8
In this investigation, 48 male rats were injected with a placebo or an akarkara (Anacyclus pyrethum) aqueous root extract at 50, 100, or 150 milligrams (mg) per kilogram (kg) of body weight for 28 days. Compared to the control group, the akarkara groups displayed significant increases in the weight of its sex organs and the sperm count in the epididymis, as well as decreases in the number of abnormal sperm.
- The researchers concluded that “the positive effects of A. pyrethrum plant on different reproductive parameters might improve the production of forthcoming drugs and dietetic components for prognosis or treatment of infertility.”9
At this time, no clinical research investigating the efficacy of akarkara on humans has been completed.
Dosage for Testosterone
- Successful clinical trials using akarkara have yet to be performed
- Typical supplements contain from 500 – 600 mg of akarkara
- Aqueous root extract
- Powdered root
- Capsule or tablet of ground root
Supplements in Review Says
- Akarkara at 500 – 600 mg daily for testosterone.
Akarkara has shown early promise as a testosterone and libido booster. Akarkara seems to have testosterone and libido-boosting effects in animals, but we still recommend waiting for clinical studies to test and verify those effects before trying it out.
Start with 500 mg of akarkara powder. If insistent on taking akarkara now, we suggest starting with a 500 mg dose.
- Annalakshmi R, et al. A treasure of medicinal herb – Anacyclus pyrethrum A review. Indian Journal of Drugs and Diseases. 2012 Jun;1(3):59-67. ↩
- Bendjeddou D, et al. Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis. J Ethnopharmacol. 2003 Oct;88(2-3):155-60. ↩
- Sharma V, et al. Evaluation of the anabolic, aphrodisiac and reproductive activity of Anacyclus pyrethrum DC in male rats. Scientia Pharmaceutica. 2009;77(1):97-110. ↩
- Chauhan NS, et al. A Review on Plants Used for Improvement of Sexual Performance and Virility. Biomed Res Int. 2014;2014:868062. ↩
- Pahuja M, et al. Root extract of Anacyclus pyrethrum ameliorates seizures, seizure-induced oxidative stress and cognitive impairment in experimental animals. Epilepsy Res. 2012 Feb;98(2-3):157-65. ↩
- Shahraki S, et al. Effects of Aqueous Root Extracts of Anacyclus pyrethrum on Gonadotropins and Testosterone Serum in Adult Male Rats. American Journal of Phytomedicine and Clinical Therapies. 2014 Jul;(2)6:767-72. ↩
- Sharma V, et al. Androgenic and spermatogenic activity of alkylamide-rich ethanol solution extract of Anacyclus pyrethrum DC. Phytotherapy Research. 2013;27(1):99-106. ↩
- Sharma V, et al. Effects of petroleum ether extract of Anacyclus pyrethrum DC. on sexual behavior in male rats. Journal of Chinese Integrative Medicine. 2010;8(8):767-73. ↩
- Shahraki MR, et al. The Effects of Aqueous Extract of Anacyclus Pyrethrum on Sperm Count and Reproductive Organs in Adult Male Rats. Zahedan Journal of Research in Medical Sciences. 2015;17(2):e1984. ↩